Article
Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes
2022-08-11
Abstract excerpt
<h4>ABSTRACT</h4> The gut microbiome of vertebrates is capable of numerous biotransformations of bile acids, which are responsible for intestinal lipid digestion and function as key nutrient-signaling molecules. The human liver produces bile acids from cholesterol predominantly in the A/B- trans orientation in which the sterol rings are “kinked”, as well as small quantities of A/B- cis oriented “flat” stereoiso...
Topics
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- Clostridium difficile and Clostridium perfringens research
- Diet and metabolism studies
- Drug Transport and Resistance Mechanisms
- Gut microbiota and health
- Helicobacter pylori-related gastroenterology studies
- Metabolism and Genetic Disorders
- Nutrition, Genetics, and Disease
- Pediatric Hepatobiliary Diseases and Treatments
Identifiers and source
- Literature Corpus work
- 6554263b-5eff-5411-95c9-85b90dc98399
- DOI
- 10.1101/2022.08.09.503364