Article

Distinct Classes of Gut Bacterial Molybdenum-Dependent Enzymes Produce Urolithins

2025-01-18

Abstract excerpt

Urolithin A is an anti-aging and anti-inflammatory gut bacterial metabolite derived from ellagic acid (EA), a polyphenol abundant in berries and nuts. The conversion of EA to urolithin A involves multiple chemically challenging phenol dehydroxylation steps that produce urolithins with varying bioactivities. Despite their biological and chemical significance, the bacterial enzymes responsible for urolithin producti...

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Literature Corpus work: 9faaf2a8-e220-5355-9ae9-83be402de7d8
DOI: 10.1101/2025.01.17.632430

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