Article

Discovery of the gut microbial enzyme responsible for bilirubin reduction to urobilinogen

2023-02-08

Abstract excerpt

The degradation of heme and the interplay of its catabolic derivative, bilirubin, between humans and their gut microbiota is an essential facet of human health. However, the hypothesized bacterial enzyme that reduces bilirubin to urobilinogen, a key step that produces the excretable waste products of this pathway, has remained unidentified. In this study, we used a combination of biochemical analyses and comparati...

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Literature Corpus work: c9c2fdbf-4287-570a-8791-35553767ce0e
DOI: 10.1101/2023.02.07.527579

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