Article
Hyperbilirubinemia syndromes (Gilbert-Meulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome).
Best practice & research. Clinical gastroenterology - 1 Oct 2010
Strassburg Christian P
Abstract excerpt
Hyperbilirubinemia is an important clinical sign that often indicates severe hepatobiliary disease of different etiologies. Inherited non-haemolytichyperbilirubinemic conditions include Dubin-Johnson, Rotor, and Gilbert-Meulengracht syndromes, which are important differential diagnoses indicating benign disease that require no immediate treatment. Dubin-Johnson and Rotor syndromes are rare, exhibit mixed direct...
Topics
- Animals
- Antineoplastic Agents, Phytogenic
- Bilirubin
- Camptothecin
- Crigler-Najjar Syndrome
- Diagnosis, Differential
- Genetic Predisposition to Disease
- Genetic Variation
- Gilbert Disease
- Glucuronosyltransferase
- Humans
- Hyperbilirubinemia, Hereditary
- Irinotecan
- Jaundice, Chronic Idiopathic
- Neoplasms
