Article
Assessing systems properties of yeast mitochondria through an interaction map of the organelle.
PLoS genetics - 20 Oct 2006
Perocchi Fabiana, Jensen Lars J, Gagneur Julien, Ahting Uwe, von Mering Christian, Bork Peer, Prokisch Holger, Steinmetz Lars M
Abstract excerpt
Mitochondria carry out specialized functions; compartmentalized, yet integrated into the metabolic and signaling processes of the cell. Although many mitochondrial proteins have been identified, understanding their functional interrelationships has been a challenge. Here we construct a comprehensive network of the mitochondrial system. We integrated genome-wide datasets to generate an accurate and inclusive...
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