Article

The GPR54 Gene as a Regulator of Puberty

2004-05-01

Abstract excerpt

The first known step in sexual maturation at puberty is the secretion of gonadotropin-releasing hormone (GnRH) by the hypothalamus. Pubertal changes also include accelerated linear growth and adrenal maturation. The authors used complementary genetic approaches in both humans and mice to study a gene ostensibly involved in the onset of puberty. Linkage analysis and candidate-gene screening were used to identify mu...

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Literature Corpus work: bcefc363-723d-51f7-9306-feaf4ff54ebf
DOI: 10.1097/00006254-200405000-00020

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