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Article

Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54.

Proceedings of the National Academy of Sciences of the United States of America - 16 Sept 2003

de Roux Nicolas, Genin Emmanuelle, Carel Jean-Claude, Matsuda Fumihiko, Chaussain Jean-Louis, Milgrom Edwin

Abstract excerpt

Hypogonadotropic hypogonadism is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of reproductive function. In the absence of pituitary or hypothalamic anatomical lesions and of anosmia (Kallmann syndrome), hypogonadotropic hypogonadism is referred to as isolated hypogonadotropic hypogonadism...

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Identifiers

PMID: 12944565
DOI: 10.1073/pnas.1834399100
PMCID: PMC196911

Genes

IHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54.PMID 12944565Read ↗

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