Article
Role of kisspeptin/GPR54 system in human reproductive axis.
Frontiers of hormone research - 1 Jan 2010
Silveira Leticia F G, Teles Milena G, Trarbach Ericka B, Latronico Ana Claudia
Abstract excerpt
The kisspeptin-GPR54 signaling complex is a key gatekeeper of human sexual maturation. Kisspeptins, encoded by the KISS1 gene, constitute a powerful stimulus for gonadotropin-releasing hormone-induced gonadotropin secretion. In addition, the KISS1 gene is a target for regulation by gonadal steroi...
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