TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.

Abstract excerpt

Major depression disorder (MDD) is a complex and chronic disease that ranks fourth as cause of disability worldwide. About 14 million adults in the USA are believed to have MDD, and an estimated 75 % attempt suicide making MDD a major public health problem. Neuroticism has been recognized as an endophenotype of MDD; however, few genome-wide association (GWA) analyses of neuroticism as a quantitative trait have...

Topics

Join the communities discussing this publication.

• Antisocial Personality Disorder
• Anxiety Disorders
• Australia
• Netherlands
• Neuroticism