Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.

Journal of molecular neuroscience : MN - 1 Jun 2013

Aragam Nagesh, Wang Ke-Sheng, Anderson James L, Liu Xuefeng

Abstract excerpt

Major depression disorder (MDD) is a complex and chronic disease that ranks fourth as cause of disability worldwide. About 14 million adults in the USA are believed to have MDD, and an estimated 75 % attempt suicide making MDD a major public health problem. Neuroticism has been recognized as an endophenotype of MDD; however, few genome-wide association (GWA) analyses of neuroticism as a quantitative trait have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antisocial Personality Disorder
Share to Anxiety Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Australia

Share to Netherlands

Share to Neuroticism

Share to Quantitative Trait, Heritable

Share to Receptors, N-Methyl-D-Aspartate

Share to Serine Endopeptidases

Source

Identifiers

PMID: 23229837
DOI: 10.1007/s12031-012-9931-1

Genes

TMPRSS9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.PMID 23229837Read ↗

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder.Semantic proximity Read ↗

Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci.Semantic proximity Read ↗

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.Semantic proximity Read ↗

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS dataSemantic proximity Read ↗

Gene-based association analysis identified 190 genes with polymorphisms affecting neuroticismSemantic proximity Read ↗

Large-scale exome sequencing identified 18 novel genes for neuroticism in 394,005 UK-based individuals.Semantic proximity Read ↗

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.Semantic proximity Read ↗

Genetic stratification of depression by neuroticism: revisiting a diagnostic traditionSemantic proximity Read ↗

Sex-Specific Genetic and Transcriptomic Liability to Neuroticism.Semantic proximity Read ↗

A whole genome association study of neuroticism using DNA pooling.Semantic proximity Read ↗

Genetic risk of major depressive disorder: the moderating and mediating effects of neuroticism and psychological resilience on clinical and self-reported depression.Semantic proximity Read ↗

Meta-analysis of genome-wide SNP- and pathway-based associations for facets of neuroticism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.