Article

Transcriptional responses to chronic oxidative stress require cholinergic activation of G-protein-coupled receptor signaling

2025-01-07

Abstract excerpt

<h4>ABSTRACT</h4> Organisms have evolved protective strategies that are geared toward limiting cellular damage and enhancing organismal survival in the face of environmental stresses, but how these protective mechanisms are coordinated remains unclear. Here, we define a requirement for neural activity in mobilizing the antioxidant defenses of the nematode Caenorhabditis elegans both during chronic oxidative stre...

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Literature Corpus work: bc6f30a1-f152-514d-8375-1fe030624b1b
DOI: 10.1101/2025.01.06.628021

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