Caenorhabditis elegans 2007: the premier model for the study of aging.

doi:10.1016/j.exger.2007.09.008

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Article

Caenorhabditis elegans 2007: the premier model for the study of aging.

Experimental gerontology - 1 Jan 2008

Johnson Thomas E

Abstract excerpt

This is the 25th anniversary of the discovery of extended longevity mutants in Caenorhabditis elegans. About one hundred papers describing results from studies on C. elegans in aging research appeared this year. Many themes were pursued including dietary restriction, daf-9 action, the role of proteolysis and autophagy, and the continued search for more Age mutants. I use the word "modulate" not "regulate" so as...

Topics

Aging
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Caloric Restriction
Gene Expression Regulation
Longevity
Models, Animal
Mutation

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Identifiers

PMID: 17977684
DOI: 10.1016/j.exger.2007.09.008
PMCID: PMC2219387

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