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Genome-wide characterization of extrachromosomal circular DNA in gastric cancer and its potential role in carcinogenesis and cancer progression

2023-01-30

Abstract excerpt

<title>Abstract</title> <p>Extrachromosomal circular DNAs (eccDNAs) carrying random genomic segments are broadly found across different cancer types, but their molecular functions and impact in gastric cancer (GC) are rarely known. In this study, we aimed to investigate the potential role of eccDNA in GC. By using the Circle-seq strategy, we observed the eccDNA abundance in gastric cancer tissues (GCT) was aberra...

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Literature Corpus work: bc6f2dac-b0cd-5924-addf-598b5b4f812d
DOI: 10.21203/rs.3.rs-2523491/v1

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