Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide characterization of extrachromosomal circular DNA in breast cancer and its potential role in carcinogenesis and cancer progression

16 Oct 2024

Abstract excerpt

Extrachromosomal circular DNAs (eccDNAs) are defined as distinct genomic entities of circular and mobile DNA molecules, but their molecular functions in and impact on breast cancer (BC) are rarely known. This study used Circle-seq to analyze eccDNAs from 19 BC tissues and 17 adjacent normal tissues. We found that eccDNAs are present on all chromosomes and enriched in seven eccDNA hotspot genes (HSGs) associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer Immunotherapy and Biomarkers
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39418165
DOI: 10.1016/j.celrep.2024.114845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide characterization of extrachromosomal circular DNA in breast cancer and its potential role in carcinogenesis and cancer progressionPMID 39418165Read ↗

Extrachromosomal circular DNA landscape of breast cancer with lymph node metastasisSemantic proximity Read ↗

eccDNAdb: a database of extrachromosomal circular DNA profiles in human cancersSemantic proximity Read ↗

Extrachromosomal circular DNA in cancer: history, current knowledge, and methodsSemantic proximity Read ↗

Extrachromosomal circular DNA (eccDNA): from carcinogenesis to drug resistanceSemantic proximity Read ↗

Extrachromosomal circular DNA: biogenesis, structure, functions and diseasesSemantic proximity Read ↗

Extrachromosomal Circular DNA: A New Target in CancerSemantic proximity Read ↗

Genome-Wide Extrachromosomal Circular DNA Profiling of Paired Hepatocellular Carcinoma and Adjacent Liver TissuesSemantic proximity Read ↗

Extrachromosomal circular DNA (eccDNA): an emerging star in cancerSemantic proximity Read ↗

Classification of extrachromosomal circular DNA with a focus on the role of extrachromosomal DNA (ecDNA) in tumor heterogeneity and progressionSemantic proximity Read ↗

Extrachromosomal circular DNA: a new potential role in cancer progressionSemantic proximity Read ↗

EccBase: A high-quality database for exploration and characterization of extrachromosomal circular DNAs in cancerSemantic proximity Read ↗

EccDNA-oriented ITGB7 expression in breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.