Article

Sequence basis of transcription initiation in human genome

2023-06-29

Abstract excerpt

Transcription initiation is an essential process for ensuring proper function of any gene, however, a unified understanding of sequence patterns and rules that determine transcription initiation sites in human genome remains elusive. By explaining transcription initiation at basepair resolution from sequence with a deep learning-inspired explainable modeling approach, here we show that simple rules can explain the...

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Literature Corpus work: bc6b587a-9406-5cdc-a74b-be7176840fcf
DOI: 10.1101/2023.06.27.546584

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