Article
Nucleotide composition-linked divergence of vertebrate core promoter architecture.
Genome research - 1 Mar 2011
van Heeringen Simon J, Akhtar Waseem, Jacobi Ulrike G, Akkers Robert C, Suzuki Yutaka, Veenstra Gert Jan C
Abstract excerpt
Transcription initiation involves the recruitment of basal transcription factors to the core promoter. A variety of core promoter elements exists; however for most of these motifs, the distribution across species is unknown. Here we report on the comparison of human and amphibian promoter sequences. We have used oligo-capping in combination with deep sequencing to determine transcription start sites in Xenopus...
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