Article

A comprehensive map of the dendritic cell transcriptional network engaged upon innate sensing of HIV

2019-03-18

Abstract excerpt

<h4>Summary</h4> Transcriptional programming of the innate immune response is pivotal for host protection. However, the transcriptional mechanisms that link pathogen sensing with innate activation remain poorly understood. During infection with HIV-1, human dendritic cells (DCs) can detect the virus through an innate sensing pathway leading to antiviral interferon and DC maturation. Here, we developed an iterativ...

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Literature Corpus work: bc43f0bd-6650-58f9-82c1-90c90e923f4a
DOI: 10.1101/579920

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