Article
Omic Technologies in HIV: Searching Transcriptional Signatures Involved in Long-Term Non-Progressor and HIV Controller Phenotypes.
Frontiers in immunology - 1 Jan 2022
De La Torre-Tarazona Erick, Ayala-Suárez Rubén, Díez-Fuertes Francisco, Alcamí José
Abstract excerpt
This article reviews the main discoveries achieved by transcriptomic approaches on HIV controller (HIC) and long-term non-progressor (LTNP) individuals, who are able to suppress HIV replication and maintain high CD4+ T cell levels, respectively, in the absence of antiretroviral therapy. Different studies using high throughput techniques have elucidated multifactorial causes implied in natural control of HIV...
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