Article

Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response

2024-12-09

Abstract excerpt

Microproteins encoded by short open reading frames (sORFs) of less than 100 codons have been predicted to constitute a substantial fraction of the eukaryotic proteome. However, relevance and roles of the majority of microproteins remain undefined because only a small fraction of these intriguing cellular players have been in-depth characterized so far. Here we use pooled overexpression screens with a library of 11...

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Literature Corpus work: bc19b034-3cb8-5c22-88cd-1c8dbb6561fb
DOI: 10.1101/2024.12.08.627409

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