Article

A large-scale sORF screen identifies putative microproteins and provides insights into their interaction partners, localisation and function

2023-06-13

Abstract excerpt

The human genome contains thousands of potentially coding short open reading frames (sORFs). A growing set of microproteins translated from these sORFs are known to have important cellular functions. However, the majority remains uncharacterised. Thus, larger screens to find functional microproteins have become more vital. Here, we performed a high-throughput CRISPR/Cas9 knock-out screen with a customised library...

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Literature Corpus work: 40392914-44f4-5c97-9891-61ef7b3ff573
DOI: 10.1101/2023.06.13.544808

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