Article

The lncRNA Snhg11, a new candidate contributing to neurogenesis, plasticity and memory deficits in Down syndrome

2023-09-25

Abstract excerpt

<title>Abstract</title> <p>Down syndrome (DS) stands as the prevalent genetic cause of intellectual disability, yet comprehensive understanding of its cellular and molecular underpinnings remains limited. In this study, we explore the cellular landscape of the hippocampus in a DS mouse model through single-nuclei transcriptional profiling. Our findings demonstrate that trisomy manifests as a highly specific modif...

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Literature Corpus work: bbf7e68b-25ed-593d-bf08-3a5b7ff7f27b
DOI: 10.21203/rs.3.rs-3184329/v1

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