Article

Using ScRNA-seq to Reveal Lymphocyte Responses to ALV-J in Bone Marrow Microenvironment

2023-05-24

Abstract excerpt

<h4>Background: </h4> The main tumors in chicken caused by avian leukemia virus (ALV) are leukemia. The bone marrow microenvironment is the genesis of leukemia, but little is known about the state of the chicken bone marrow microenvironment under avian leukemia virus subgroup J (ALV-J) infection. Meanwhile, alterations in the immune status of the bone marrow microenvironment are closely associated with the develop...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0a029417-4e00-58ab-8f93-2931edda58cf
DOI: 10.21203/rs.3.rs-2866250/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Using ScRNA-seq to Reveal Lymphocyte Responses to ALV-J in Bone Marrow MicroenvironmentDOI 10.21203/rs.3.rs-2866250/v1Read

Integrated analysis of lncRNA and mRNA repertoires in Marek’s disease infected spleens identifies genes relevant to resistanceSemantic proximity Read

MeDIP-Seq and RNA-Seq Releaved TGFB2 Associated with Disease Resistance to ALV-J Infection in ChickensSemantic proximity Read

The <i>MYC</i> , <i>TERT</i> , and <i>ZIC1</i> Genes Are Common Targets of Viral Integration and Transcriptional Deregulation in Avian Leukosis Virus Subgroup J-Induced Myeloid LeukosisSemantic proximity Read

Comparison of single-cell landscapes among three amniotes reveals conservation and innovation in avian immune systemsSemantic proximity Read

The Roles of MicroRNAs (miRNAs) in Avian Response to Viral Infection and Pathogenesis of Avian Immunosuppressive DiseasesSemantic proximity Read

Cross-species comparison of single-cell landscapes reveals conservation and innovation in chicken immune systemsSemantic proximity Read

Identification of Resistance Loci to Avian Leukosis via Genome-Wide Association Analysis in Chengkou Mountain ChickensSemantic proximity Read

GADD45β, an anti-tumor gene, inhibits avian leukosis virus subgroup J replication in chickens.Semantic proximity Read

A single-nucleus census of immune and non-immune cell types for the major immune organ systems of chickenSemantic proximity Read

Exploration of Alternative Splicing (AS) Events in MDV-Infected Chicken Spleens.Semantic proximity Read

Innate Immune Responses in ALV-J Infected Chicks and Chickens with Hemangioma In VivoSemantic proximity Read

Autophagy-mediated TET2 degradation by ALV-J Env protein suppresses innate immune activation to promote viral replicationSemantic proximity Read