Article
<i>In situ</i> transcriptional profile of a germinal center plasmablastic burst hints at <i>MYD88/CD79B</i> mutants-enriched Diffuse Large B-cell Lymphomas
2021-07-31
Abstract excerpt
The germinal center (GC) reaction results in the selection of B-cells acquiring effector Ig secreting ability by progressing towards plasmablastic differentiation. This transition is associated with exclusion from the GC microenvironment. The aberrant expansion of plasmablastic elements within the GC fringes configures an atypical condition, the biological characteristics of which have not been defined yet. We inv...
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Identifiers and source
- Literature Corpus work
- 60ad0592-1e2a-518c-baaa-bc3624f44e52
- DOI
- 10.1101/2021.07.28.21261117
