Article

A novel age-informed approach for genetic association analysis in Alzheimer’s disease

2021-01-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Many Alzheimer’s disease (AD) genetic association studies disregard age or incorrectly account for it, hampering variant discovery. <h4>Method</h4> Using simulated data, we compared the statistical power of several models: logistic regression on AD diagnosis adjusted and not adjusted for age; linear regression on a score integrating case-control status and age; and multivari...

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Literature Corpus work: bba700f5-93ba-57a8-9b81-22d41b8a47b2
DOI: 10.1101/2021.01.05.21249292

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