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Article

The impact of non-additive genetic associations on age-related complex diseases

2020-05-14

Abstract excerpt

Genome-wide association studies (GWAS) are not fully comprehensive as current strategies typically test only the additive model, exclude the X chromosome, and use only one reference panel for genotype imputation. We implemented an extensive GWAS strategy, GUIDANCE, which improves genotype imputation by using multiple reference panels, includes the analysis of the X chromosome and non-additive models to test for as...

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Literature Corpus work
2cdde7c2-fb45-545b-a4a1-f658f5389d6b
DOI
10.1101/2020.05.12.084608
Open publication

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The impact of non-additive genetic associations on age-related complex diseasesDOI 10.1101/2020.05.12.084608
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