Article

Integrating human plasma proteomes with genome-wide association data implicates novel proteins and drug targets for Rheumatoid arthritis

2024-10-17

Abstract excerpt

<title>Abstract</title> <p>Background Genome-wide association studies (GWAS) have uncovered over 100 loci associated with Rheumatoid arthritis (RA) risk. However, how these loci contribute to RA risk remains largely unknown, which has hampered the development of new therapeutics. To identify genes contributing to RA risk through their effects on protein abundance, we conducted the first large-scale proteome-wide...

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Literature Corpus work: ba3c5e54-2eb6-5198-bd1c-c71a7d7764fd
DOI: 10.21203/rs.3.rs-4974860/v1

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