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Article

Plasma proteins and rheumatoid arthritis: A Mendelian randomization analysis.

Medicine - 31 Oct 2025

Lu Chuan, Huang Xiao-Xiao, Lu Xin, Huang Ming, Xu Jianwen

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic, progressive inflammatory systemic autoimmune disease with incompletely understood etiology, causing substantial global disease burden. This study aimed to identify plasma proteins associated with RA using Mendelian randomization (MR) of large-scale plasma proteomics, providing potential biomarkers and therapeutic targets for early diagnosis and personalized treatment. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41261583
DOI: 10.1097/MD.0000000000045647
PMCID: PMC12582758

Genes

ATF6
C2
USP25
AIF1
CXCL16
DNASE1L2
HMBS
HS3ST3A1
MAPK3
PRSS57
TNFAIP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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