Article
Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis.
Arthritis research & therapy - 22 Jan 2021
Wu Cuiyan, Tan Sijian, Liu Li, Cheng Shiqiang, Li Peilin, Li Wenyu, Liu Huan, Zhang Feng'e, Wang Sen, Ning Yujie, Wen Yan, Zhang Feng
Abstract excerpt
OBJECTIVE: To identify rheumatoid arthritis (RA)-associated susceptibility genes and pathways through integrating genome-wide association study (GWAS) and gene expression profile data. METHODS: A transcriptome-wide association study (TWAS) was conducted by the FUSION software for RA considering EBV-transformed lymphocytes (EL), transformed fibroblasts (TF), peripheral blood (NBL), and whole blood (YBL). GWAS...
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