Article

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis

2020-10-08

Abstract excerpt

<h4>Objective: </h4> To identify rheumatoid arthritis (RA) associated susceptibility genes and pathways through integrating genome-wide association study (GWAS) and gene expression profile data. <h4>Methods: </h4> A transcriptome-wide association study (TWAS) was conducted by the FUSION software for RA considering EBV-transformed lymphocytes (EL), transformed fibroblasts (TF), peripheral blood (NBL) and whole bloo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 90de4737-6c2e-5614-ba95-27bee3d08be1
DOI: 10.21203/rs.3.rs-86447/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritisDOI 10.21203/rs.3.rs-86447/v1Read

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis.Semantic proximity Read

Gene-Based Genome-Wide Association Analysis in European and Asian Populations Identified Novel Genes for Rheumatoid Arthritis.Semantic proximity Read

Synovial transcriptome-wide association study implicates novel genes underlying rheumatoid arthritis riskSemantic proximity Read

[Genome-wide association study for rheumatoid arthritis].Semantic proximity Read

Identification of Key Immune-Related Genes, Molecular Pathways and Immune Infiltration as Diagnostic and Therapeutic Candidate Targets for RA: an integrated bioinformatics-based analysisSemantic proximity Read

Large-scale meta-analysis across East Asian and European populations updated genetic architecture and variant-driven biology of rheumatoid arthritis, identifying 11 novel susceptibility loci.Semantic proximity Read

Novel insight into the aetiology of rheumatoid arthritis gained by a cross-tissue transcriptome-wide association study.Semantic proximity Read

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.Semantic proximity Read

Integration of scRNA-Seq and Bulk RNA-Seq Reveals Molecular Characterization of the Immune Microenvironment in Rheumatoid ArthritisSemantic proximity Read

Genetics of rheumatoid arthritis contributes to biology and drug discovery.Semantic proximity Read

Synovial transcriptome-wide association study implicates novel genes underlying rheumatoid arthritis risk.Semantic proximity Read

Analyzation of the Peripheral Blood Mononuclear Cells Atlas and Cell Communication of Rheumatoid Arthritis Patients Based on Single-Cell RNA-SeqSemantic proximity Read