Article

Identifying therapeutic targets for rheumatoid arthritis by genomics-driven integrative approaches

2024-03-20

Abstract excerpt

<h4>Summary</h4> Genomics-driven drug discovery framework holds promise in developing novel therapeutic targets. Here, we leveraged large-scale genomic data including genome-wide association studies (GWAS), rare variant burden tests in exome sequencing studies (Exome), and protein quantitative trait loci (pQTL), to prioritize potential therapeutic targets and identify opportunities for drug repositioning in rheuma...

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Literature Corpus work: 4aa10a53-f852-5a06-83a9-8aae0adad062
DOI: 10.1101/2024.03.19.24304536

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