Article

Astrocytic CREB in nucleus accumbens promotes susceptibility to chronic stress

2024-01-16

Abstract excerpt

<h4>Background</h4> Increasing evidence implicates astrocytes in stress and depression in both rodent models and human Major Depressive Disorder (MDD). Despite this, little is known about the transcriptional responses to stress of astrocytes within the nucleus accumbens (NAc), a key brain reward region, and their influence on behavioral outcomes. <h4>Methods</h4> We used whole cell sorting, RNA-sequencing, and b...

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Literature Corpus work: ba3bf292-3edc-5cb7-b8f8-b615ff432d61
DOI: 10.1101/2024.01.15.575728

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