Article

Electroconvulsive stimuli reverse neuro-inflammation and behavioral deficits in a mouse model of depression

2023-05-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Electroconvulsive therapy is a fast, safe, and effective treatment for severe clinical depression but there is an ongoing search for mechanistic insights. <h4>Methods</h4> We used a mouse neuro-endocrine model of depression to examine behavioral, cellular, and molecular effects of electroconvulsive stimuli (ECS). <h4>Results</h4> The behavioral response to repeated ECS cor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: df678048-5087-5248-85f4-161b9349001b
DOI: 10.1101/2023.05.13.540577

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Electroconvulsive stimuli reverse neuro-inflammation and behavioral deficits in a mouse model of depressionDOI 10.1101/2023.05.13.540577Read

Epigenetic Effects of Electroconvulsive SeizuresSemantic proximity Read

Electroconvulsive Seizures Regulate Gene Expression of Distinct Neurotrophic Signaling PathwaysSemantic proximity Read

Electroconvulsive stimulation drives cortical spreading depression dependent immediate early gene expression in miceSemantic proximity Read

Repetitive Neuronal Activation Regulates Cellular Maturation State via Nuclear ReprogrammingSemantic proximity Read

A Clinically Aligned Murine Model of Electroconvulsive Stimulation Reverses Social Aversion and Displays Fear Memory Impairment After Chronic Social Defeat StressSemantic proximity Read

Not so different after all: a systematic review of rodent electroconvulsive therapy (ECT) models in translational chronic stress and depression researchSemantic proximity Read

Integrative Mouse and Human mRNA Studies Using WGCNA Nominates Novel Candidate Genes Involved in the Pathogenesis of Major Depressive DisorderSemantic proximity Read

Regional distribution of cellular of molecular pathways in a mouse model of Gulf War illness by Single-Cell RNA Sequencing AnalysisSemantic proximity Read

Repetitive Neuronal Activation Regulates Cellular Maturation State via Nuclear ReprogrammingSemantic proximity Read

Spatiotemporal remodeling in the habenula marks the onset of depressionSemantic proximity Read

Genetic fate mapping of type-1 stem cell-dependent increase in newborn hippocampal neurons after electroconvulsive seizures.Semantic proximity Read

Astrocytic CREB in nucleus accumbens promotes susceptibility to chronic stressSemantic proximity Read