Article

Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling

2024-06-25

Abstract excerpt

Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear. Here, we probed the diversity of ∼145,000 total human cortical astrocytes with single nucleus and spatial transcriptomics, showing that human astrocytes comprise a molecularly and anatomically diverse cell population. In individuals with p...

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Literature Corpus work: eca1b936-53d2-55f4-91ed-4295c23e34ff
DOI: 10.1101/2024.06.24.600362

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