Article

Astrocytic CREB regulates transcriptional, neuronal, and behavioral responses to cocaine

2025-06-08

Abstract excerpt

Drug addiction is characterized by neuronal adaptations that support a shift from goal-directed behaviors to habitual, compulsive drug-seeking with persistent effects on cognition and decision-making. Emerging evidence increasingly indicates that astrocytes are also involved in nervous system disorders, including addiction, but the cocaine-induced astrocyte-specific transcriptome has not yet been investigated. We...

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Literature Corpus work: 147c322a-632b-5919-adbf-f4c07813402a
DOI: 10.1101/2025.06.04.657899

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