Article

Nucleus accumbens neuron subtype translatome signatures in socially stressed females

2025-06-01

Abstract excerpt

Major depressive disorder (MDD) disproportionately affects women, yet the molecular mechanisms underlying female vulnerability remain poorly understood. The nucleus accumbens (NAc), a reward circuitry hub, is central to stress- and depression-related pathology. While NAc medium spiny neuron (MSN) transcriptional adaptations have been characterized in stressed male rodents, much less is known about female adaptatio...

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Literature Corpus work: 7d4d44da-ee9d-539b-a0b3-22716a566b1e
DOI: 10.1101/2025.06.01.656319

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