Article

Cellular morphology emerges from polygenic, distributed transcriptional variation

2026-03-13

Abstract excerpt

Height and most disease risk are known polygenic traits: characteristics governed by multiple genes at different loci instead of a select few. Though we are beginning to understand how genetic variation impacts cell morphology, whether such an analogous polygenic architecture operates at the cellular level, where morphology integrates cytoskeletal organization, organelle positioning, and metabolic state, has yet t...

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Literature Corpus work: ba1f6641-063a-54a1-a6bd-1bd98cb1119a
DOI: 10.64898/2026.03.12.711281

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