Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ExPRSweb: An online repository with polygenic risk scores for common health-related exposures.

American journal of human genetics - 6 Oct 2022

Ma Ying, Patil Snehal, Zhou Xiang, Mukherjee Bhramar, Fritsche Lars G

Abstract excerpt

Complex traits are influenced by genetic risk factors, lifestyle, and environmental variables, so-called exposures. Some exposures, e.g., smoking or lipid levels, have common genetic modifiers identified in genome-wide association studies. Because measurements are often unfeasible, exposure polygenic risk scores (ExPRSs) offer an alternative to study the influence of exposures on various phenotypes. Here, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lipids

Share to Multifactorial Inheritance

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 36152628
DOI: 10.1016/j.ajhg.2022.09.001
PMCID: PMC9606385

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ExPRSweb: An online repository with polygenic risk scores for common health-related exposures.PMID 36152628Read ↗

ExPRSweb - An Online Repository with Polygenic Risk Scores for Common Health-related ExposuresSemantic proximity Read ↗

Integration of risk factor polygenic risk score with disease polygenic risk score for disease prediction.Semantic proximity Read ↗

Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.Semantic proximity Read ↗

Challenges and Opportunities for Developing More Generalizable Polygenic Risk Scores.Semantic proximity Read ↗

An integrative analysis of genomic and exposomic data for complex traits and phenotypic predictionSemantic proximity Read ↗

An integrative analysis of genomic and exposomic data for complex traits and phenotypic prediction.Semantic proximity Read ↗

Poly-Exposure and Poly-Genomic Scores Implicate Prominent Roles of Non-Genetic and Demographic Factors in Four Common Diseases in the UKSemantic proximity Read ↗

From Data Curation to Risk Reporting: A Pipeline for Polygenic Risk ScoresSemantic proximity Read ↗

A Scalable Framework to Integrate Social Determinants of Health into Disease Risk Models using Biobank Survey DataSemantic proximity Read ↗

Leveraging pleiotropy to improve genetic risk prediction across diseasesSemantic proximity Read ↗

PolyGenie: a reproducible Nextflow pipeline for phenome-wide association studies using polygenic risk scores.Semantic proximity Read ↗

Implementation of Individualised Polygenic Risk Score Analysis: A Test Case of a Family of FourSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.