Article

Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data

2023-10-14

Abstract excerpt

Assay for Transposase-Accessible Chromatin sequencing (ATAC-Seq) is a widely used technique to explore gene regulatory mechanisms. For most ATAC-Seq data from healthy and diseased tissues such as tumors, chromatin accessibility measurement represents a mixed signal from multiple cell types. In this work, we derive reliable chromatin accessibility marker peaks and reference profiles for most non-malignant cell type...

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Identifiers and source

Literature Corpus work: b9fbdaab-4a6c-57f4-b191-299f889dee0e
DOI: 10.1101/2023.10.11.561826

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