Article

Defining the Regulatory Logic of Breast Cancer Using Single-Cell Epigenetic and Transcriptome Profiling

2024-06-17

Abstract excerpt

<h4>SUMMARY</h4> Annotation of the cis -regulatory elements that drive transcriptional dysregulation in cancer cells is critical to improving our understanding of tumor biology. Herein, we present a compendium of matched chromatin accessibility (scATAC-seq) and transcriptome (scRNA-seq) profiles at single-cell resolution from human breast tumors and healthy mammary tissues processed immediately following surgica...

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Literature Corpus work: 92c0b398-629b-5aa3-8548-86127532134d
DOI: 10.1101/2024.06.13.598858

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