Article

FSP1 and histone deacetylases suppress cancer persister cell ferroptosis

2025-08-25

Abstract excerpt

Cancer persister cells populate minimal residual disease and contribute to acquired drug resistance. We previously discovered that persister cells are sensitized to ferroptosis. However, our understanding of this emergent persister cell vulnerability remains limited, impeding ferroptosis drug development efforts. Here, we sought to understand key factors which govern persister cell ferroptosis to inform combinator...

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Identifiers and source

Literature Corpus work: b9ec7341-c59b-5eae-a991-e4554472ee7e
DOI: 10.1101/2025.08.21.671520

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