Article
Ferroptosis Resistance: Redundant Antioxidant Networks Is a Barrier to Cancer Therapy
2026-05-12
Abstract excerpt
Ferroptosis is an iron-dependent, lipid peroxidation–driven form of regulated cell death that has emerged as a promising strategy to eliminate therapy-resistant cancers. However, both intrinsic and acquired resistance to ferroptosis-inducing agents (FINs) limit their clinical efficacy. From this perspective, an integrated model is proposed in which ferroptosis resistance emerges through coordinated redox, metaboli...
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Identifiers and source
- Literature Corpus work
- 6f696b69-1a81-56ce-88ed-109c4f524a0c
- DOI
- 10.20944/preprints202605.0698.v1