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Metabolic orchestration of drug-tolerant persister cells in cancer

1 Dec 2024

Abstract excerpt

Despite significant advancement in developing effective anticancer therapies, drug resistance remains a major clinical obstacle to achieving durable cures. This has sparked extensive research efforts into the underlying mechanisms of acquired resistance to cancer treatment, unveiling genetic alterations, dysregulated signaling pathways, and intricate interactions within the tumor microenvironments. However, the...

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Cancer, Hypoxia, and Metabolism
Microtubule and mitosis dynamics
Pancreatic function and diabetes

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39872154
DOI: 10.1093/lifemedi/lnae040

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