Article
Dysregulation of cellular iron predisposes chemotherapy resistant cancer cells to ferroptosis
2024-12-10
Abstract excerpt
<h4>ABSTRACT</h4> Despite centuries of research, metastatic cancer remains incurable due to resistance against all conventional cancer therapeutics. Alternative strategies leveraging non-proliferative vulnerabilities in cancer are required to overcome cancer recurrence. Ferroptosis is an iron dependent cell death pathway that has shown promising pre-clinical activity in several contexts of therapeutic resistant c...
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Identifiers and source
- Literature Corpus work
- 21fdd122-3a5b-5213-871f-f3ee817a6efb
- DOI
- 10.1101/2024.12.05.626685