Article

Induced B-Cell Receptor Diversity Predicts PD-1 Blockade Immunotherapy Response

2024-12-04

Abstract excerpt

<h4>ABSTRACT</h4> Immune checkpoint inhibitors such as anti-PD-1 antibodies (aPD1) can be effective in treating advanced cancers. However, many patients do not respond and the mechanisms underlying these differences remain incompletely understood. In this study, we profile a cohort of patients with locally-advanced or metastatic basal cell carcinoma undergoing aPD-1 therapy using single-cell RNA sequencing, high-...

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Literature Corpus work: b9d5d415-090b-519a-a17e-7b52e76fa86d
DOI: 10.1101/2024.12.03.626669

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