Article

DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy

2021-01-11

Abstract excerpt

Cancers evade the immune system in order to grow or metastasise through the process of cancer immunoediting. While immune checkpoint inhibitors have been effective for reactivating tumour immunity in some types of cancer, many other solid cancers, including breast cancer, remain largely non-responsive. Understanding the way non-responsive cancers evolve to evade immunity, what resistance pathways are activated and...

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Literature Corpus work: 27a79b06-3b45-58d7-9dee-430d72143143
DOI: 10.1101/2021.01.11.426174

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