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Lower DNA methylation levels in CpG island shores of <i>CR1, CLU</i>, and <i>PICALM</i> genes in the blood of Alzheimer’s disease patients

2020-03-17

Abstract excerpt

The aim of the present study was to (1) investigate the relationship between late onset AD and DNA methylation levels in the top six Alzheimer’s disease (AD)-related genes in blood and (2) examine its applicability to the diagnosis of AD. We examined methylation differences at CpG island shores in the top six genes using Sanger sequencing, and one of two groups of 48 AD patients and 48 elderly controls was used fo...

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Literature Corpus work
b9d53cfc-be87-5317-a60e-5ec4ad4ee6be
DOI
10.1101/2020.03.14.20035683
Open publication

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Lower DNA methylation levels in CpG island shores of <i>CR1, CLU</i>, and <i>PICALM</i> genes in the blood of Alzheimer’s disease patientsDOI 10.1101/2020.03.14.20035683
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