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Whole genome methylation sequencing in blood from persons with mild cognitive impairment and dementia due to Alzheimer’s disease identifies cognitive status

2024-09-27

Abstract excerpt

<h4>INTRODUCTION</h4> Whole genome methylation sequencing (WGMS) in blood identifies differential DNA methylation in persons with late-onset dementia due to Alzheimer’s disease (AD) but has not been tested in persons with mild cognitive impairment (MCI). <h4>METHODS</h4> We used WGMS to compare DNA methylation levels at 25,244,219 CpG loci in 382 blood samples from 99 persons with MCI, 109 with AD, and 174 who a...

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Literature Corpus work
eecc0c87-6731-541c-81b4-5a54ac4e4294
DOI
10.1101/2024.09.26.615196
Open publication

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Whole genome methylation sequencing in blood from persons with mild cognitive impairment and dementia due to Alzheimer’s disease identifies cognitive statusDOI 10.1101/2024.09.26.615196
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