Article

Haplotype Analysis Reveals Pleiotropic Disease Associations in the HLA Region

2024-07-31

Abstract excerpt

The human leukocyte antigen (HLA) region plays an important role in human health through involvement in immune cell recognition and maturation. While genetic variation in the HLA region is associated with many diseases, the pleiotropic patterns of these associations have not been systematically investigated. Here, we developed a haplotype approach to investigate disease associations phenome-wide for 412,181 Finnis...

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Literature Corpus work: b9cec4b4-053c-5057-99ff-8291995f7614
DOI: 10.1101/2024.07.29.24311183

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