Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

What has GWAS done for HLA and disease associations?

International journal of immunogenetics - 1 Oct 2017

Kennedy A E, Ozbek U, Dorak M T

Abstract excerpt

The major histocompatibility complex (MHC) is located in chromosome 6p21 and contains crucial regulators of immune response, including human leucocyte antigen (HLA) genes, alongside other genes with nonimmunological roles. More recently, a repertoire of noncoding RNA genes, including expressed pseudogenes, has also been identified. The MHC is the most gene dense and most polymorphic part of the human genome. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Diseases, Inborn
Share to Genome, Human
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-B Antigens

Share to HLA-DR Antigens

Share to Linkage Disequilibrium

Share to Major Histocompatibility Complex

Share to RNA, Untranslated

Source

Identifiers

PMID: 28877428
DOI: 10.1111/iji.12332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

What has GWAS done for HLA and disease associations?PMID 28877428Read ↗

Genetic Association in the HLA Region.Semantic proximity Read ↗

Major histocompatibility complex genomics and human disease.Semantic proximity Read ↗

Interrogating the major histocompatibility complex with high-throughput genomics.Semantic proximity Read ↗

Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease.Semantic proximity Read ↗

HLA allele-calling using whole-exome sequencing identifies 129 novel associations in 11 autoimmune diseases: a multi-ancestry analysis in the UK BiobankSemantic proximity Read ↗

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.Semantic proximity Read ↗

Human MHC architecture and evolution: implications for disease association studies.Semantic proximity Read ↗

Haplotype Analysis Reveals Pleiotropic Disease Associations in the HLA RegionSemantic proximity Read ↗

HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases.Semantic proximity Read ↗

HLA genomics in the third millennium.Semantic proximity Read ↗

An update of the HLA genomic region, locus information and disease associations: 2004.Semantic proximity Read ↗

The human Major Histocompatibility Complex as a paradigm in genomics research.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.