Article

A role for the ATP-dependent DNA ligase Lig E of Neisseria gonorrhoeae in biofilm formation

2023-09-24

Abstract excerpt

The ATP-dependent DNA ligase Lig E is present as an accessory DNA ligase in numerous proteobacterial pathogen genomes, including many disease-causing species. Here we have constructed a genomic Lig E knock-out in the obligate human pathogen Neisseria gonorrhoeae and characterised its growth and infection characteristics. This demonstrates that N. gonorrhoeae Lig E is a non-essential gene and its deletion does no...

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Literature Corpus work: b96d6478-a192-580e-9f1d-b68e62cff4ce
DOI: 10.22541/au.169553705.52290420/v1

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