Article

A role for the ATP-dependent DNA ligase Lig E of <i>Neisseria gonorrhoeae</i> in biofilm formation

2023-09-20

Abstract excerpt

<h4>ABSTRACT</h4> The ATP-dependent DNA ligase Lig E is present as an accessory DNA ligase in numerous proteobacterial genomes, including many disease-causing species. Here we have constructed a genomic Lig E knock-out in the obligate human pathogen Neisseria gonorrhoeae and characterised its growth and infection characteristics. This demonstrates that N. gonorrhoeae Lig E is a non-essential gene and its deleti...

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Literature Corpus work: c24ef173-d5fb-5582-b337-88ef8553b106
DOI: 10.1101/2023.09.19.558522

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